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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59ca0be0b3a20cb1a3c3e058aa45b8bc96c0329a9a0d350a1495f948be7f1832' 
  AND token = 'cxv7zdTGAVVOK2/CyZhZBTcWtoyMbA/WAOK7DdO+ejs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}