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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f81f55593a70773403f429caee5ee132f9ea76a3e1e73f06eca6b3d1a1a0ae5' 
  AND token = '+0Fa+i3NcgIpG2LnuGioHbiiTyEzEnv7UnE/1VylCSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}