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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '222dd4aebea6424122e4ba648750ac5efdf06f65c87278e461214a17b00aa3c9' 
  AND token = '5Is9+28rywjCQ5OfbdRPG0XjoQHdBtU68KpjIjoANKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}