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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0ad634162173a12e2fa957100d050daf41d8c25e2247fd07abd2f119ff2d650' 
  AND token = 'E+1RUXvTCrW0OJiv4sv0wlv6Lm+lG9bvY3j2i59UOhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}