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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e43c77cde62c2e13699c4ad5297bf79046708fe1501b7b13ae645959c651c41' 
  AND token = 'o7UZqsIWKiqqwmcJgW+zuaLD4qROyuzOxdvbZEp9LQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}