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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e8d10731c957d679b0966fa5cc08d2053ce4e4db148e6ff9fa36cbb5020aa03' 
  AND token = 'YsixnT5Oq5oLqdR/BLzo+Ztkx892K1kfZ7WG6BAUOs8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}