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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21844dcc7812459163a7f9c44591ce85941dcfa267f3794dbd4bb5f4cbbe0ee5' 
  AND token = 'aK1tw4kXrA0MjcRtWnLk9R4AvX8znleHsBjZoq1zfrs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}