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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5627bf161a905788e54c292f63a71db27ce2374d1155d2166732e6645cf8035' 
  AND token = 'DtU4Jau4ehSCdE67TE4SZmQIHrYlB91CoZ7LSLULjLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}