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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '141ca57d4e516f0c747c384a63055ac97745be7cbbb58bc7e7eceab9901ea316' 
  AND token = '+0tf75Z80Fr2CkMJDivbQHunTsqTkhavjbq7p/QESFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}