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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c06053c50a64a090ab94f3121d74e57f19fa3e8920626af34c12e3fc4755c09f' 
  AND token = 'p4tDkL0ylUa+njzumxb3Y0PSvmkx+02gKfAj6N7Xd3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}