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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80dc46f07c853aebe75a0f19d0b07a1f39807a8eadcd8f4a38e66fb1e012b17d' 
  AND token = 'tjEbH0JdhC10D+HEFkY9d/W2TKoy1f6n9rRqJhHszM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}