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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22bcf4e513c61b84672c6869360338615580c7758a8be5aabd5ad5f1bb9079d8' 
  AND token = 'O3lc8NNWVaH/wMYfFCat3NOhrQo/FNgBlOUHCGU3JNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}