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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5297a6948160d1c2a5c6504f2b603dfaf6dbc0f0d2768af93d9a78042d99a47' 
  AND token = 'HRKJ6kCM4ba3XYeLc1y7xRWpH3aOOgbzPNn8uBy9acQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}