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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2a9c1e59b84595eac8beb1fdecbbde035383c00f8e925130d88ef071e502378' 
  AND token = 'DdGbUL3UfDsWXCb1iRFzKVZoy3yXhn4K251StQrmDO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}