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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59ce821cd2c619ea1be99f5fe133e6ad23189b12558f126bbfb6653b728d4dc6' 
  AND token = '6tjmRnZpHw85GKPVw9wiE3qhLcNlBVTwMj3DpSb/f90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}