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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd351ed2ef77fe94d5b7ad047bdec39fc10e95f13bc6dabf61f3457961d158789' 
  AND token = 'tE9NWmcRfzSdUkNBtMjT7bHi/5VxXhthEYLbkc6NuZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}