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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1f887d56d13b54e72c3c24b71c53b6f1f61ff8d01d0159fba985614fa8b4ce7' 
  AND token = 'QdEUTHbFtOOiS9n67NHd1MWTe/c3NQen9qQ6RtjJkdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}