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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ea0988d8a9560f7664732f9924e3e5cdc9337d3cdddaca0daedfdb361330101' 
  AND token = 'JMq68w46SUx9NB3DDItP31USKFB1c9PsnapvTMlL7W4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}