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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3917c1f7ee3a36deea5760b20a2c0c6c3adf9cfe25c175d8d82ecac41fd4a5e9' 
  AND token = '+Y+lmmWf2OmmNFtNjGwoxMXj7dcJcqVhst/nt3rzUBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}