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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'caea3a676684495a46a9ae932ca337dbb995b0126baa54a8982f760f45f7df22' 
  AND token = '9U2ccxFkC91SKTRsk3VotPI4w/v+f2AEO27eHMhDucE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}