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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cbd4ce43ff05d026d2aa5a8d79a13cf053b7e5362b8feef0bc8ea8f35f1621e' 
  AND token = 'PfhTho2GdKwcQn3XcPjw1COv6Mc6Sv2/37xHdi7DMPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}