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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2266bd8b0b10a16f51184aeec25a116097587e06f32e0e2a4de3c22714e01de5' 
  AND token = 'bi/r1fV31Nb+7QjrYEiVNp1OezfLyGAHR0g3I6VOcKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}