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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33ed4ac38e5478071c0f771206fd328bd2253ec14ff6ec7c8926de5b7b4a7fd0' 
  AND token = '8VpBTYWATtvtZ9IGfKrGH9VyV7V67j84rP38PCAsQsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}