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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c108df0e3ab96705d2626efc665eb327c7c31b73f77231b233a255211561b32c' 
  AND token = 'fUSO/f0uwaEWaBE+gh+2XJOken4qHYtpHHpTqkOMyLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}