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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efd6ca5dc974f89e369dc9c19add8231b75c1ca09b6111c504df3f6e29893437' 
  AND token = 'd2PYpgkugK5eh7A5k2w+Ybk6WntjhdnxB67JAxeC+IM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}