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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64cd4638a637ebb8b503f26db8ea17c0be0cbf17117c863f62b122e9d9a8529e' 
  AND token = 'uG+onEb4CXHr/+R71GMnIXFQ8MfD0zYgwQ7L5Tu/Pqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}