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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bfb54ae6c244ed00c34bc009a0f9d80b397fde46497902d41bf1666b767cd49' 
  AND token = 'jw/9y+LxX5pTWRNACY5l0mv0fC8qFsQWWOgQ723kXwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}