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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49a8b72a3b3b561cbda50e36761fc9ffee596f5fbfd8640a45d9951b7d43f444' 
  AND token = 'DhvDywbaOJRLE3CudZGrdCSuo7IWBL9D3r2Q4TBZKAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}