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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0e8a0f6a82ed71f09480fdfc161e65261b778b779128d2a6d88f6573babb199' 
  AND token = 'P7hTqJcp0btRtik53VRGaGkc3fcVluZG7TgXt4UsIJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}