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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b55a0f5cedfbca4caba64bbb50ae68af0fa6de1310447b8a4ac0055eb3a2639' 
  AND token = 'MSE5U5CPIhmlmNYQ40CTz2DuTdEXNtkT2LjAMqS9Wz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}