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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d690f63b1f9df4de3180ab6aa375c4da19c55d0b783bd5672725aaa3b11be6f' 
  AND token = '0VmTM6OGY+a2v8HLU1KeQTWY6DeWsQvfmP2xyoj7jh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}