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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '728f5b16bd2e9cd9269f2eaa2b6bdd930739ad1d15e65a57bf781e8f05e9d00b' 
  AND token = 'UAy+izLJePhidf59tYRon+ecG59H9pessxmg7GZnrLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}