SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22d4bfe8bbe04819d9db2f711dfe1b8ee9f1a5f4a1b446d1ea41d981843d0442' 
  AND token = 'fEYCTzTQSYZVFD+JhyL18NsApOlFYh0TrRhhyMbMork=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}