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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69972ac0229c99a178f5e39260c832d51e5d5afd4657d2af95df8deede35f17a' 
  AND token = 'rz/xJEPXXngyoIxBVw6nkweg6OnvJe01zkhX48g1HRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}