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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43e84be89f8e8ece0d82895956c67c31a408c410f606c788ba36bdf8bb3a7f69' 
  AND token = 'JLbleRe372B32jiAlOlPMJrcL15Yb5rBry4nW34D2es=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}