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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b5ac9799793a300af960cf0c981de643e7cd3b883ed1ccee4941b1bf48635ce' 
  AND token = '46X9MkJKDttXo+KMk472T3ofz/Jk8qZXdr8ULqHIYyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}