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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd259d375859a525d456d91bb0db92ee6e184e23f2c79d35be1c0eaf380b5bc4' 
  AND token = 'F9bE12vnC/kZ+C9ZT3Xf84rIRf+RfCK6BQ4lHTGb1gI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}