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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80ff1776fe405b23626b1a316c74a2ee687a26588c654f17d1e1931cf02fee35' 
  AND token = 'FAEV46qnuuVKNAV5M7PzWuSLKvEKhazLeelMgFjNfqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}