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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ee4bc1a884be7399dcfa365a589e422f32a222a2e6c5e0f2592d5834339e2b8' 
  AND token = '+CF0cSqJM5AgoOtVFXEVDxUhg7zNayDidR+6vCWJSUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}