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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '442e0a4187fb88631b346710a5cafce2ba9891131bcfd3e09222c326ddf00260' 
  AND token = 'FGOW4nSJFMQ6FVAQie/3vXHmekosg5dI7bi0iLP36DM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}