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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5724b63c49b2d1bc258d9c53def64c0156115bb1eaaedeee3467c4ade679b48' 
  AND token = 'wyLi7xRWBEmk124Pz1uyXr84y2xscqwjDfAuz1G9t/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}