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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da0d1035fb5059287d155dcda7a0f1d42ef5f899c4bf2ae38689b07df41cc707' 
  AND token = 'r6mtQ6TGwVkOMqh1jH40FHqbD/DyNoD/t3MqCVqu+ak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}