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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3afdd9da5100555d9ff3f75eb9d7c3a7e0f01bab07946b1bf5682db12f567604' 
  AND token = 'CupUpozRNX+ucC61idAF21Bd70SMxvAbnZt+f9VfsT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}