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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2bd2f5126f46fb94b3a13b86c3de89a15d649780850a91734a7913f94cd581c' 
  AND token = 'cEB8uy0aMFPOAVFtv+tlTFXrMcE3hs9cnxnN4jH4Ya4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}