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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f72d9646d0e8a7299d79d1ab0d7f886a5415eaddf82f058bd9566c1424bf6cee' 
  AND token = 'GwM5UtU/Pb63Rk67hV4UOpuyYW1WN1dsnSMaD4akY14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}