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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fcb1c4840be523e8137284a4d83e3f0fef582e23c1f4d53c3e8801a6aec5ac63' 
  AND token = 'PHk33AmV/qlQb/mzJ+OGkc5pAY/YvMgp6Ubb38YFhdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}