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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a50dec72731a5ef372889db82b9138f73ce08ef5c718f37bfa9016ce0e08a2e1' 
  AND token = 'm6NqyFc+ZETqYXEPjDTaeltPw3z28glf3UYSjr1aOSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}