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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff4e0ea72179a0410eb76ba888cdc1369981b8113ff7adf639413697bcb17e07' 
  AND token = '6vxc2udU9CoTC1rabez+oqis24fuIwK8YjrRd2ZOUWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}