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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80416795306dd4f17ae07fcec09603d7c3152a12002587eeee4302314a4378f3' 
  AND token = 'VAeyFx3mkG0lO/eHNbIUqsvlJnImCB7C7qTkYC1/gXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}