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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5285f24f44636c3f18a244e23a397c12f103d215ab2e8923a1d715d8d4277b5' 
  AND token = 'LFmr4d/8v03mReiIdFXFY+E7GFAb6ZtOmujUTuiPQ0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}